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Dear Friend of PDF:

What do the latest headlines mean for Parkinson’s science? See our team’s take on the latest studies covering genetics, a gene therapy treatment, clinical research improvements and more.

Genetic Parkinson’s May Progress More Slowly

Does a certain type of early-onset Parkinson’s progress more slowly than classic PD?

According to a PDF-funded study published online November 4 in JAMA Neurology, people who develop Parkinson’s because of mutations in a gene called parkin better retained movement and cognitive abilities after years with the disease, than did people with non-inherited PD.  Find out how this might help some people to better plan for the future.
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Gene Therapy Technique Shows Early Promise for PD

Can a new surgical technique that uses gene therapy successfully reprogram brain cells to produce the dopamine lost in PD?

An early stage study published in the January 10 issue of The Lancet says yes, indicating that the surgery is safe and potentially effective in improving movement symptoms in people with advanced PD. Find out what it means, and what research needs to come next.
Learn More

Research Study Participants in US Report Positive Experiences

What do clinical research participants think of their experiences, and how can this help us improve trials? Thousands of volunteers in the US rated their experiences as mostly positive, according to a study that appeared in the December 5 online edition of the New England Journal of Medicine.

PDF sees this study as an important first step in developing ways to incorporate the patient perspective into research. But, we also think the results indicate room for improvement. Find out why.
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If you have questions about these reports, please feel free to contact PDF's HelpLine at (800) 457-6676 or info@pdf.org, Monday through Friday from 9:00 AM to 5:00 PM ET.

Dr. James Beck
Vice President, Scientific Affairs,
Parkinson’s Disease Foundation

PDF's work in Parkinson's research, education and advocacy is made possible by your contributions. Make a donation today to support our mission. Thank you for your generosity.

If you have or believe you have Parkinson’s disease, then promptly consult a physician and follow your physician’s advice. This email is not a substitute for a physician’s diagnosis of Parkinson’s disease or for a physician’s prescription of drugs, treatment or operations for Parkinson’s.

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